VaccinesSara KaranJun 12, 20141 min readUpdated: 17 hours agoThis article was restored from an archived copy; part of the original text could not be recovered.Anti-CD47 (removes cancer’s “Invisibility cloak”)Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell responseStanford School of Medicine, Institute for Stem Cell Biology and Regenerative Medicine - CD47ImMucine (Vaxil)Vaxil reports promising results from its follow-up clinical trial of ImMucin in multiple myeloma a patients.Vaxil Reports Positive Results From a Phase I/II Clinical Trial Using Its Therapeutic Cancer Vaccine, ImMucin, In Patients With Multiple Myelomahttp://www.cancer.gov/clinicaltrials/search/view?cdrid=761257&version=HealthProfessional&protocolsearchid=6371711IscomatrixISCOMATRIX adjuvant links adaptive and innate immune reponsesISCOMATRIX Adjuvant Combines Immune Activation with Antigen Delivery to Dendritic Cels in Vivo Leading to Effective Cross-Priming of CD*+T CellsSaponin-based adjuvants create a highly effective anti tumor vaccine when combined with in situ tumor distruction.
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